Nobuhito Araki Selected Research

Synovial Sarcoma (Synovioma)

8/2019	Favorable outcomes of localized synovial sarcoma patients with a high utilization rate of neoadjuvant and/or adjuvant chemotherapy.
1/2017	Therapeutic potential of TAS-115 via c-MET and PDGFRα signal inhibition for synovial sarcoma.
12/2016	Functional and therapeutic relevance of hepatocyte growth factor/c-MET signaling in synovial sarcoma.
10/2016	Trabectedin is a promising antitumour agent for synovial sarcoma.
9/2014	Deflection of vascular endothelial growth factor action by SS18-SSX and composite vascular endothelial growth factor- and chemokine (C-X-C motif) receptor 4-targeted therapy in synovial sarcoma.
5/2014	Tailored therapeutic strategies for synovial sarcoma: receptor tyrosine kinase pathway analyses predict sensitivity to the mTOR inhibitor RAD001.
1/2014	Clinical outcomes for patients with synovial sarcoma of the hand.
4/2010	Downregulation of SS18-SSX1 expression in synovial sarcoma by small interfering RNA enhances the focal adhesion pathway and inhibits anchorage-independent growth in vitro and tumor growth in vivo.
12/2006	Expression of claudin7 is tightly associated with epithelial structures in synovial sarcomas and regulated by an Ets family transcription factor, ELF3.
7/2004	Crisscross CTL induction by SYT-SSX junction peptide and its HLA-A*2402 anchor substitute.

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Nobuhito Araki Research Topics

Disease

43	Neoplasms (Cancer) 06/2020 - 05/2002
33	Sarcoma (Soft Tissue Sarcoma) 01/2020 - 10/2002
13	Synovial Sarcoma (Synovioma) 08/2019 - 08/2002
9	Neoplasm Metastasis (Metastasis) 03/2019 - 06/2005
8	Osteosarcoma (Osteogenic Sarcoma) 01/2019 - 01/2004
6	Ewing Sarcoma (Sarcoma, Ewing) 09/2017 - 07/2008
4	Chondrosarcoma 12/2017 - 11/2002
4	Infections 04/2014 - 01/2013
3	Liposarcoma 01/2020 - 02/2010
3	Clear Cell Sarcoma 01/2020 - 06/2014
3	Myxoid Liposarcoma 09/2017 - 06/2010
3	Rhabdomyosarcoma 11/2008 - 05/2002
2	Chordoma 05/2019 - 05/2016
2	Disease Progression 03/2016 - 04/2015
2	Nausea 04/2015 - 05/2012
2	Fatigue 05/2012 - 11/2011
2	Lipoma (Lipomata) 02/2010 - 06/2009
2	Malignant Fibrous Histiocytoma 08/2004 - 05/2002
1	Chondroblastoma 03/2020
1	Leiomyosarcoma 01/2020
1	Vascular Remodeling 01/2020
1	Fistula 05/2019
1	Spinal Cord Compression 03/2019
1	Femoral Fractures (Femoral Fracture) 09/2017
1	Breast Neoplasms (Breast Cancer) 01/2017
1	Osteoid Osteoma 09/2016
1	Pneumothorax 05/2016
1	Thrombocytopenia (Thrombopenia) 05/2016
1	Compression Fractures (Compression Fracture) 03/2016
1	Pancreatic Neoplasms (Pancreatic Cancer) 03/2016
1	Extraskeletal Myxoid Chondrosarcoma 01/2016
1	Necrosis 01/2016
1	Mesenchymal Chondrosarcoma 01/2016
1	Margins of Excision 05/2015
1	Hypophosphatemia 07/2014
1	Rare Diseases (Rare Disease) 07/2014
1	Oncogenic osteomalacia 07/2014
1	Familial Hypophosphatemia (Phosphate Diabetes) 07/2014
1	Pseudarthrosis (Pseudoarthrosis) 03/2013
1	Prosthesis Failure 01/2013
1	Complex Regional Pain Syndromes 01/2013

Drug/Important Bio-Agent (IBA)

8	TrabectedinIBA 01/2020 - 04/2015
7	pazopanib FDA Link 01/2017 - 05/2012
7	Proteins (Proteins, Gene)FDA Link 04/2015 - 05/2002
6	Ifosfamide FDA LinkGeneric 06/2015 - 01/2004
6	Doxorubicin (Adriamycin)FDA LinkGeneric 06/2015 - 01/2004
3	eribulin FDA Link 01/2020 - 01/2017
3	Messenger RNA (mRNA)IBA 05/2006 - 11/2002
2	Pharmaceutical PreparationsIBA 01/2020 - 04/2015
2	Biological ProductsIBA 12/2017 - 10/2016
2	Gemcitabine FDA Link 03/2016 - 08/2014
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 09/2014 - 04/2013
2	Everolimus FDA Link 08/2014 - 05/2014
2	AntigensIBA 06/2014 - 05/2005
2	Tyrosine Kinase InhibitorsIBA 06/2014 - 05/2012
2	Methotrexate (Mexate)FDA LinkGeneric 02/2013 - 01/2004
2	Cisplatin (Platino)FDA LinkGeneric 02/2013 - 01/2004
2	Transcription Factor CHOPIBA 02/2012 - 02/2010
2	CCAAT-Enhancer-Binding ProteinsIBA 02/2012 - 02/2010
2	HLA-A24 AntigenIBA 07/2004 - 08/2002
2	Peptides (Polypeptides)IBA 07/2004 - 08/2002
1	Bone SubstitutesIBA 03/2020
1	Microphthalmia-Associated Transcription FactorIBA 01/2020
1	Diphosphonates (Bisphosphonates)IBA 09/2017
1	Denosumab FDA Link 09/2017
1	Antineoplastic Agents (Antineoplastics)IBA 09/2017
1	4- (2- fluoro- 4- ((((2- phenylacetyl)amino)thioxomethyl)amino)phenoxy)- 7- methoxy- N- methyl- 6- quinolinecarboxamideIBA 01/2017
1	Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA 12/2016
1	Alanine Transaminase (SGPT)IBA 04/2015
1	CXC ChemokinesIBA 09/2014
1	LigandsIBA 09/2014
1	MTOR InhibitorsIBA 08/2014
1	Docetaxel (Taxotere)FDA Link 08/2014
1	pyridinium 3-methoxyestra-1,3,5(10)-trien-6-yl sulfate (PMTS)IBA 07/2014
1	Fibroblast Growth Factor-23IBA 07/2014
1	S100 Proteins (S 100 Protein)IBA 06/2014
1	Melanins (Melanin)IBA 06/2014
1	Activating Transcription Factor 1IBA 06/2014
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 05/2014
1	PolymersIBA 01/2013

Therapy/Procedure

20	Drug Therapy (Chemotherapy) 01/2020 - 01/2004
12	Therapeutics 12/2017 - 10/2004
11	Limb Salvage 06/2020 - 10/2008
8	Prostheses and Implants (Prosthesis) 01/2020 - 10/2008
7	Heavy Ion Radiotherapy 01/2020 - 02/2016
6	Radiotherapy 09/2017 - 01/2004
4	Surgical Amputation (Amputations) 07/2013 - 03/2003
3	Adjuvant Chemotherapy 08/2019 - 01/2004
2	Reoperation 04/2014 - 03/2013
2	Arthrodesis 03/2013 - 10/2008
2	Arthroplasty 03/2013 - 02/2011
1	Decompression 03/2019
1	Precision Medicine 01/2019
1	Conservative Treatment 09/2017
1	Radiofrequency Ablation 09/2016
1	Chemoradiotherapy 03/2016
1	Bone Transplantation (Bone Grafting) 03/2014
1	Lymph Node Excision (Lymph Node Dissection) 01/2014
1	Oral Administration 04/2013
1	Thrombolytic Therapy 01/2013